INDICATIONS AND USAGE:
For the treatment of adult patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). In combination with azacitidine, or decitabine, or low-dose cytarabine for the treatment of newly diagnosed acute myeloid leukemia (AML) in adults 75 years or older, or who have comorbidities that preclude use of intensive induction chemotherapy. DOSAGE AND ADMINISTRATION :Recommended Dosage for Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: Week 1 Venetoclax Daily Dose 20 mg Week 2 50 mg Week 3 100 mg Week 4 200 mg Week 5 and beyond 400 mg Recommended Dosage for Acute Myeloid Leukemia: Day 1 Day 2 Day 3 Days 4 and beyond Venetoclax Daily Dose 100 mg 200 mg 400 mg 400 mg orally once daily of each 28 day cycle in combination with Azacitidine or Decitabine
Tyrosine kinase inhibitor
B-cell lymphoma-2 (BCL-2) inhibitors
Tyrosine kinase inhibitor
thymidine-based nucleoside analogues
polymerase (PARP) inhibitors
Tyrosine kinase inhibitor
Tyrosine kinase inhibitor
Tyrosin Kinase Inhibitor (TKI)
Tyrosine kinase inhibitor
Tyrosine kinase inhibitor