INDICATION
• Benign gastric and duodenal ulcers including those complicating NSAID therapy
•Erosive reflux esophagits
•Hypersecretion disorder of gastric acid
•Zollinger-Ellison syndrome.
 

DOSAGE AND ADMINISTRATION
Benign gastric and duodenal ulcers including those complication NSAID therapy : 20 mg daily for 4 weeks in duodenal ulcer or 8 weeks in gastric ulcer, in severe cases the dose may be increased to 40 mg daily; long-term use is not recommended.
 

Healing of reflux esophagitis : 20 mg daily for 4 weeks, followed by a further 4-8 weeks if not fully healed; 40 mg daily has been given for 8 weeks in reflux esophagitis refractory to other treatment; may be continued at 20 mg daily.
 

Zollinger-Ellison syndrome : Initially 60 mg once daily; usual range 20-120 mg daily (above 80 mg in 2 divided doses). Larger doses of upto 180 mg daily in divided doses may be used or as prescribed by the physicians.

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